Monday, May 15, 2017

Angus Single-Step Has Launch Date

Angus Genetics Inc will switch to single-step genomic prediction on July 7th.

Since 2010 they have been using multi-step genomic prediction. In multi-step, genomic predictions are treated as correlated traits to produce GE-EPDs. In single-step, all genomic, pedigree, and performance data is analyzed in one model. The key to calculating EPDs is measuring genetic similarity. Traditional EPDs used pedigree data to estimate genetic similarity. In single-step, genomic data more accurately measures relatedness, i.e. genetic similarity. The pedigree and genomic relationship measures are combined.

Since November, AGI has evaluated multi-step vs single-step. They have seen very similar accuracies between the two methods. But, single-step tends to have slightly higher accuracies. Further, there are several advantages to single-step. These advantages include removing the need to recalibrate and using all of the data simultaneously.

Watch for further information from Angus about the switch to single-step as July 7th approaches.

Friday, May 12, 2017

Hair Shedding Update and Reminders

It is the time of year to once again record and report hair shedding scores. This fact sheet on should come in handy.

Participants in our hair shedding genomic research project should have received an email from Harly Durbin. This email contained an Excel file to report hair shedding scores on enrolled cattle. If not, please get in touch with us as soon as possible. We must receive 2017 data in these Excel files!

It is important that we receive data on our target goal of 8,000 cattle. If your cattle are enrolled in the research program, we should have received DNA cards and 2016 data from you by now. If we have not yet received your data, you are in danger of being removed from the program. If we have not received your data, please get in touch with Harly and I by email or by phone.

We know receiving genomic-enhanced EPDs is very important to hair shedding study participants. This is also a priority to us. We have worked with breed associations and GeneSeek to make this happen.

For IGS breed associations, we are sending genotypes from Mizzou to Mahdi Saatchi, IGS’s genomic scientist. We are still working out how the data will be formatted when we send the data between Mizzou and IGS. For other breed associations, we are sending genotype data directly from GeneSeek to the breed association.

Many participants will start to receive GE-EPDs for their animals in the next few weeks.

Please be patient with us. We are not a service provider. This is our first time sharing research genotypes with breed associations. So, we are forging a new path. Please stick with us as we create tools to select more heat tolerant and sustainable cattle.

Please contact us with any questions or concerns. Or, see our FAQ page.

We appreciate your help and interest in this project!

Game Changers

by Ron Locke
R & J Ranch, Long Lane

All professions require their members to attend periodic continuation training to stay abreast of innovations in their given fields. While some may argue “Cattlemen” or Cow/Calf Producers are not professions, I strongly disagree.  For the sake of argument and space let’s assume I’m right and skip the several paragraphs of justification to that end. We cattlemen need to know how to improve our operations and that requires keeping ourselves informed.
In the past few weeks I have attended several conferences and came to the conclusion there are three “gamechangers” currently available in our industry that are being overlooked by most cattle producers and they are having a significant impact on their bottom lines day in and day out.
The first “gamechanger” is toxic fescue and its insidious drain on cattle performance from birth to death. With years of research at numerous universities and thousands of herds examined and assimilated we know every animal eating toxic K-31 fescue is being affected and more importantly we know there is no silver bullet that will prevent the toxin from lowering conception rates or reducing the weight gain loss we unknowingly experience when animals consume it. There are studies being conducted in genetics which may prove some cattle are better than others on K-31 but it is very doubtful we will find a breed that is immune to the toxin. The only certain way to rid our herds of the losses is to eliminate toxic K-31 from our pastures. The new “toxic friendly” or novel fescues have proven they will perform as well as the old K-31 in harsh conditions and cattle will not incur any of the problems consuming them. The longer you wait to eradicate your toxic fescue the more money you are leaving in the fields.
Bottom Line: You can raise conceptions rates in your herd by 15-20% and increase weight gains on all cattle by over ½ pound per day per animal! It’s impossible to justify, “it’s too costly to eradicate my toxic fescue”, when just the opposite is true.
The second “gamechanger” is fixed time artificial insemination (FTAI). In the past few years we have seen FTAI become more prevalent in the beef industry. Now with a new protocol called Split Time AI we have breeding by appointment with a reduction of drugs used and improved conception rates. Everyone understands a calf born at the beginning of the calving season weighs more than a calf born at the end of the season. At 2 pounds per day that can easily amount to over 100 pounds per calf born early over those late calves and at $1.50 a pound every calf born early puts extra dollars in your pocket. With split time AI you can see over 60% of your calves born in the first 16 days of calving season which I can personally attest to.
Bottom Line: Split Time AI will condense your calving window, significantly improve your herd genetics, and put more pounds on your calves by sale day translating to more money in your pocket!

Lastly, the third “gamechanger” is Genetic testing. Most registered herd/seed stock breeders have been using genetic testing for many years. Now we can test most all animals, providing informed expected progeny differences, (EPD’s) on our commercial cattle like registered cattle. I’ve heard countless producers tell me they can look at an animal and tell “XYZ”.  I have witnessed many of these same producers put to the test with live animals and DNA testing results proving you can’t.  You simply can’t look at an animal and tell what its next 10-20 calves will weigh at birth or at weaning or how big their ribeye’s will be or nearly anything else for that matter. But EPD’s will with certain degrees of accuracy depending on the trait. If your calves weigh 500 pounds at weaning now and you select a bull with a high weaning weight EPD your calves could easily weigh 550 at weaning next year.  If you are retaining heifers for your herd you may want to focus on heifers that score higher in calving ease maternal (CEM), heifer pregnancy (HP), milk, etc. These traits can be determined the day the heifer calf is born by simply taking a drop of blood from the ear and placing it on a “blood card” and sending it to the appropriate testing lab for your breed/crossbred of cattle. Results are normally back within 30 days, long before you need to market the animals. At weaning time you can select the best heifer calves in your herd to retain and sell the rest.
Bottom Line: For less than $50 with some basic test costing as little as $17 you can determine the value of a calf to your operation about a month after they are born.

I have some experience with each of these topics and would be glad to answer any questions you may have however for more detailed advice I encourage you to contact the specific experts listed below and incorporate these gamechangers into your operation increasing your profitability in the coming years!

Toxic Fescue: Dr. Craig Roberts,  State Forage Ext Specialist & Professor Plant Sciences University of Missouri
 Web profile

Split Time AI:  Dr. David Patterson, State Beef Reproduction Ext Specialist & Professor of Animal Science University of Missouri
Web profile

Genetics: Dr. Jared Decker, State Beef Genetics Ext Specialist & Assistant Professor University of Missouri
Web profile

Thursday, May 11, 2017

Now HIRING! Looking for talented postdoctoral fellow

My group is currently recruiting a postdoctoral fellow.

We are looking for candidates who are passionate about genetics, genomics, and research. Ideal candidates are creative, hard working (while maintaining a work/life balance), and self starters. Our group is strictly computational, so candidates should enjoy working on computers and analyzing data. Candidates should have programming experience (typically in R, Python, Perl, Julia, etc.) and be familiar with the command line. Candidates will need to demonstrate ability to write well and publish research.

We currently have access to over 48,000 genotyped beef cattle with phenotypes and breeding values from breed associations (see Decker, 2015). We are currently negotiating to obtain access to an additional 300,000 genotyped cattle. These samples are in addition to tens of thousands of animals genotyped by the University of Missouri researchers (see Google Scholar profile for examples of data sets). We also have access to whole genome sequencing data from over 2,000 cattle. So, if you like working with lots of data, come join us! Our group uses population genomics to better understand the  history of cattle breeds and to inform future selection decisions. We are interested in local genetic adaption, fertility, inbreeding, and, of course, genomic prediction. We have a large USDA-funded project focusing on local adaption in cattle. With our collaborators, we also enjoy projects looking at the evolution of quail, buffalo, and catfish.

Candidates interested in science communication and extension will also have opportunities to develop these skills.

We hope to fill the position as soon as possible, but hiring the right candidate will be the priority.

Interested candidates should contact Jared Decker, either by email, phone, or Twitter. Please include your CV and references.

As a mentor, my focus is helping you achieve your career goals. I have an open door policy and routinely touch base with my students. We have weekly joint lab meetings with Jerry Taylor's group and Bob Schnabel's group. I have an annual meeting with each mentee to discuss career plans, 5 and 10 year plans, progress, professional development goals, etc. I would be happy to put you in touch with my current graduate students so they can tell you more about my mentorship style and what working in my group is like.

Please contact me if you would like more information about this position.

The University of Missouri is an Equal Opportunity/Affirmative Action employer. To request ADA accommodations, please contact Amber Cheek, JD our Director of ADA Education and Accessibility at 573-884-7278 (V/TTY).

Wednesday, May 10, 2017

Monday, April 17, 2017

eBEEF Monday: Simple Inheritance in Beef Cattle

Managing traits controlled by simple inheritance has economic importance to many beef operations. Understanding simple inheritance can assist producers in breeding cattle that are the phenotype desired, such as polled, or avoid undesirable traits, such as lethal defects. This information sheet explains how simple inheritance works and how it can be managed.

See Fact Sheet for more information on Simple Inheritance in Beef Cattle.

Monday, April 10, 2017

eBEEF Monday: Parentage Testing

Parentage testing can be a valuable tool for both seedstock breeders and commercial producers.  This fact sheet covers how parentage testing works and tips for using parentage testing successfully. Parentage testing is often thought of as a tool that is only applicable to seedstock producers, but in fact, there are benefits to commercial producers as well. Parentage testing not only ensures correct pedigree, but can provide information to make important management decisions for commercial producers. Knowing some of the basics of parentage testing and how it works can help a producer understand the benefits of testing.

See Fact Sheet for more information about Parentage Testing.