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Showing posts from June, 2013

Comparison of updated Angus GE-EPD tests

As you may know, both Zoetis and GeneSEEK have updated their genomic tests.

Zoetis still uses about 50,000 SNPs, but have now trained their data set with more animal records and genotypes. The genetic correlations for the Zoetis test range from 0.38 to 0.73. See this Angus Journal article for more information.

GeneSeek now use about 80,000 SNPs in its genomic test. The genetic correlations for the GeneSeek test range from 0.60 to 0.70 for most traits, except milk which is at about 0.4 and calving ease direct which is at 0.34. See this explanation from the American Angus Association.

So, the accuracy differences appear to be pretty small.

Both tests cost $75. If you add genetic abnormality tests, such as AM, NH, or CA, to the Zoetis test, you pay $23.00 per test. If you add an the same genetic abnormality tests to the GeneSeek test, you pay $8.00 per test. See the Angus Genetics Inc. website or https://www.angusonline.org/AGI/AgiDnaPricing.aspx for more details.

Scientific Hype Cycle

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I was recently told that I was being over exuberant in my promotion of genomic technologies. If I have slipped into hyperbole, it has been for two reasons: a) An unintentional mistake. b) Push back against the disillusionment of a valid technology.

In previous decades new DNA technologies, such as microsatellites, AFLP markers, etc, lead to a lot of hype about how the beef industry was going to be radically changed by these DNA technologies. These were the "Technology Trigger" and "Peak of Inflated Expectations" in the diagram above. I've previously described that these single gene DNA tests completely under-performed compared to expectations. Consequentially, the "Peak of Inflated Expectations" was followed by the "Trough of Disillusionment". In this period of disillusionment, two important things happened. First, Meuwissen, Hayes, and Goddard proposed a new way to use DNA markers to predict genetic merit. Rather than looking at individual…