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Hereford and Red Angus Heifers Recruited for Genomics Research

The University of Missouri is recruiting 2,500 Hereford heifers and 2,500 Red Angus heifers to participate in a heifer puberty and fertility genomic research project. Heifers should be registered Hereford, registered Red Angus, or commercial Hereford or Red Angus. Hereford x Red Angus crossbred heifers targeted for the Premium Red Baldy Program would also be a good fit for the research project. Producers must be willing to work with a trained veterinarian to collect the following data: ReproductiveTract Scores collected at a pre-breeding exam 30 to 45 days prior to the start of the breeding season. PelvicMeasurements (height and width) collected at the same pre-breeding exam 30 to 45 days prior to the start of the breeding season. Pregnancy Determination Using Ultrasound reporting fetal age in days. Ultrasound will need to occur no later than 90 days after the start of the breeding season. In addition, heifers must have known birth dates and have weights recorded eithe
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BIF Genetic Prediction: Genetic Evaluations at International Genetic Solutions

Mahdi Saatchi
International Genetic Solutions

IGS has data from about 15 different breed associations. They have 180,000 genotyped animals in the evaluation. Two years ago, they have 65,000 animals genotyped in IGS. Most of these were males. So, in the last two years they have almost tripled this number and have added many more females, through programs such as Cow Herd Roundup.

IGS uses the BOLT software developed by Theta Solutions. This software allows many different types of models to be fit. IGS fits the single-step hybrid model. In single-step BLUP, you blend the pedigree relationships with the genomic relationship to have a single relationship matrix. In single-step hybrid you blend the genotypes and pedigree to infer genotypes for every animal in the pedigree. They then use the marker effects to estimate breeding values.

In their genetic evalution they use a subset of markers that they have identified as predictive in multiple breeds. This subset of markers provides more accurate predictions compared to using all 50,000 markers.

Saatchi performed validation work comparing the old system to the new hybrid BOLT model. He used data collected prior to 2015 and validated in data collected after 2015. The new hybrid BOLT model was more accurate.

IGS uses multi-breed and complex models to achieve more accurate genetic predictions.
IGS wants to add new traits such as heifer pregnancy and feed efficiency. They also want to continue to refine which markers are included in their marker subset.
Location: Kansas City, MO, USA

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