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Showing posts with the label marker-assisted selection

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Dr. Jamie Courter is your Mizzou Beef Genetics Extension Specialist

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By Jared E. Decker Many of you have probably noticed that things have been a lot less active on the A Steak in Genomics™   blog, but you probably haven't known why. In January 2021, I was named the Wurdack Chair in Animal Genomics at Mizzou, and I now focus on research, with a little bit of teaching. I no longer have an extension appointment. But, with exciting news, the blog is about to become a lot more active! Jamie Courter began as the new MU Extension state beef genetics specialist in the Division of Animal Sciences on September 1, 2023. I have known Jamie for several years, meeting her at BIF when she was a Masters student. I have been impressed by Jamie in my interactions with her since that time.  Dr. Courter and I have been working closely together the last 6 weeks, and I am excited to work together to serve the beef industry for years to come! Jamie holds a bachelor’s degree in animal science from North Carolina State University and earned a master's degree in animal...
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Diagnostic for Disease Susceptibility in Sheep

Here is an article about the discovery and utilization of genetic markers to reduce the susceptibility of sheep to ovine progressive pneumonia virus. From  Viral Infection in Sheep Linked to Gene : "Producers could use the marker we’ve made available to make a flock genetically less susceptible to disease, and therefore, decrease the risk of animals becoming infected again over time," Leymaster says.   The ultimate goal is to give producers tools that allow them to choose breeding stock that do not have genetic risk factors, he says, so they can reduce the prevalence of OPPV and eventually eradicate it from flocks.    " We don’t want to oversell these findings, but at the same time, we want producers to consider how they might use this to their advantage," Leymaster says. "We’re continuing our research and will be able to contribute additional information in the future. I’m optimistic that the industry will be able to successfully address this major dis...
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Asking the Right Questions...

Drovers Cattle Network recently shared this  video  in which they discussed the recent changes at Igenity.  The conversation continued by discussing strategies (and products) to reduce risk and select the best replacement heifers and cows during drought conditions.  So, that got me interested in the products referred to by Dr. Jim Gibb.  A quick search lead me to here and here on Igenity's website.  At the end of the second link it says: Have more questions? Let an expert give you the inside information — igenity.support@neogen.com So, what questions should beef producers be asking?  As we previously discussed , some beef genomic technologies return valuable information (tests for traits with genes of large effect, genomic selection) and some do not (gene tests predicting a complex trait with a small number of markers).  Following are some questions (and suggested actions) to get you started: 1. Has the test been validated by the NCBEC? ...
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Gene Tests vs Genomic Selection

Two different paradigms have existed regarding the use of DNA markers in animal breeding. The first strategy is gene tests, also referred to as marker assisted selection (MAS).  The second is genomic selection. Gene Test Gene tests attempt to predict a trait or breeding value based on the results (genotypes) of a small number of DNA markers. These tests are either developed using a candidate gene approach or from genome-wide analyses.  In a candidate gene approach, a scientist assumes which genes influence a trait and investigates variants within those genes for an association with the trait of interest.  These assumptions can be wrong and a scientist may identify an association by random chance.  In a genome-wide approach, a scientist makes no assumptions about which genes influence the trait, but analyzes markers evenly spaced throughout the genome. Genomic Selection In genomic selection, thousands of evenly spaced DNA markers are genotyped in a large po...
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